HW4: Case-Control Studies
- Due Oct 4, 2021 at 3pm
- Points 100
- Questions 20
- Available after Sep 27, 2021 at 5pm
- Time Limit None
Instructions
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20 Questions; 5 points each; 100 total points. Please have the below Scenario and Tables accessible while you take this homework.
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Scenario A: In a case-control study by Doll et al (R. Doll and A. B. Hill, 'Smoking and carcinoma of the lung: preliminary report', BMJ, 1950;2:746), investigators compared the smoking history of a group of hospitalized patients with lung cancer with the smoking history of a similar group without lung cancer. Data for this study were collected from hospitalized patients in London and the surrounding communities over a four-year period (April 1948 to February 1952). Hospital personnel at more than 20 hospitals were asked to contact investigators whenever a patient was admitted with a new diagnosis of lung cancer. These patients were then interviewed about their smoking habits. Investigators interviewed a sample of patients from the same hospitals to identify controls at the outset of the study (note that some of these controls could eventually become cases), but with different illnesses, about their smoking habits.
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Table 1
Smokers
Non-smokers
Total
Cases
1350
7
1357
Controls
1296
61
1357
Total
2646
68
2714
-Table 2
Cigarettes smoked daily
Cases
Controls
Odds Ratio
0
7
61
Reference
1-14
565
706
X
15-24
445
408
Y
25 +
340
182
Z
Total
1,357
1,357